The contemporary era is an exciting decade for the healthcare industry as acquisitions and mergers pertaining to healthcare innovations are heating up. Statistics reveal that there have been 43 acquisitions with internet brands, which have allowed WebMD to be on the top list and earn a profit of $2.8 billion. While the current era of technological reform is leaving significant footprints in almost all domains of life, advancements in the healthcare industry are worth highlighting. At present, the DNA/RNA sequencing and analysis software are widely utilized in the healthcare industry in order to quantify gene expression. From exhaustive research to meaningful data acquisition, predicting diagnosis to effective treatment, innovations in the healthcare sector have done remarkably well in recent years. So what is the scope of contemporary techniques such as DNA sequencing and analysis, Big Data analysis,etc.in reforming the healthcare industry? The answer to the question is quite simple; the advent of biological tools and software have significantly lowered costs, enhanced revenues for healthcare systems, reduced wait duration and has ensured the provision of high-quality care to the common masses. Thus, it is high time for the common masses to familiarize themselves with cutting-edge trends in the healthcare sector.
Let us have a look at the top five next-generation sequencing applications and the importance of these advancements in the domain of healthcare.
DNA Sequence Assembler is a revolutionary and unique software tool for performing automatic DNA assemblies like manuals, DNA sequence analysis, automated processing, content editing, file format conversion, and mutation detection. Over the past decade, the application of Next-Generation Sequencing (NGS) in particular DNA sequence analysis software have evolved and have incorporated revolutionary innovations to tackle the complexities of genomes.
For its unsurpassed price and ease of use, DNA is based on the most modest selection for alignment of DNA sequence. The DNA sequence analysis software will do all the work for you. Among other things, it charges:
- Automatically detect and mark low-quality zones for the sample DNA.
- Automatically detect adjustment sequences
- Automatically correct ambiguities of your contigs
- Automatically save to your computer Container and project
- With DNA Baser only it will take exactly 5 (five) seconds to move from a single sinus dovetail (to the final result).
With the Baser DNA sequence analysis software, you can also:
- Assemble multiple DNA strands or mix them with one regency string
- Assembled by lots and alignment of groups of segments by name
- Import and analyze files from ABI, SCF, FASTA, SEQ, TXT, GBK files
- View and edit section
According to the latest research report published by BIS research institute entitled “Global Precision Medicine Market – Analysis and Forecast (2017-2026)” the market of precision medicine will transform the world of healthcare entirely and is anticipated to earn a profit of at least $141.7 billion by the end of 2026. Although the term ‘precision medicine’ might sound unfamiliar to you, the technique has gained momentum in the healthcare industry due to its immense perspective to transform the current health standards. Precision medicine is an emerging approach, which involves a thorough screening of the genetic makeup of an individual to evaluate the susceptibility of a number of diseases for which a tailored therapeutic treatment can then be devised. The concept of precision medicine is being adopted by the healthcare agencies and is an amalgamation of the expansion of numerous innovative technologies such as
- Molecular biomarker analysis
- Next-generation sequencing
- DNA Sequencing and analysis
- Big data analytics etc.
This innovative technological approach has proliferated successfully in the past decade and has opened new doors for preventing chronic diseases including neurological disorders, diabetes, cancer, and other cardiovascular diseases.
One of the groundbreaking medical innovations of the current decade is 3-D printing. 3-D printing has been implemented in various healthcare facilities to design patient-specific healthcare products such as implants, airway stents, and prosthetics. These customized designs facilitate efficient performance while ensuring the comfort of patients as they are modeled in accordance with the body measurement of patients. 3-D printing has been widely utilized in surgical planning such as face transplant or heart surgery, where the end goal is to offer the nominal risk of postoperative complications.
DNA sequencing and analysis requires dicing the DNA sequences to acquire high-coverage, short-read sequence data but this greatly compromises the structural features of the genome. Likewise, RNA genetic abnormalities can be screened out using the novel technique of RNS therapeutics. RNA therapeutics eradicates genetic abnormalities before they are translated into non-functioning or function proteins. A few applications of this innovation include RNA interference, antisense nucleotides and it is successfully employed to treat cancer, rare genetic diseases, and neurologic illnesses.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is one of the breakthrough advancements in the medical world. Tools that use CRISPR utilize DNA sequencing and analysis software which is based on the principle of imitating the natural immunity mechanism of the bacterial cell of invading viruses, which can then in turn splice the infected DNA strands. CRISPR is an innovative technology in the healthcare sector, which has become a powerful tool for editing genomes. It has assisted researchers in altering the DNA sequences and consequently examines their underlying functions. The CRISPR technology has offered countless potential applications in the field of medicine, which range from identifying and amending gene defects, treating and preventing the spread of disease, and enhancing the yield and quality of crops.
In conclusion, all DNA sequence analysis software is based on the assumption that highly similar DNA fragments originate from the same position within the genome. In this way, the similarity between DNA sequences is used to connect individual fragments into longer contiguous sequences, called contigs (consensus sequences obtained from the assembly of the reads). NGS, in particular DNA sequencing and analysis software, has reformed the protocols and procedures of healthcare today by offering cost-efficient, robust and accurate diagnostic and treatment options
Wakai, T., Prasoon, P., Hirose, Y., Shimada, Y., Ichikawa, H., &Nagahashi, M. (2019). Next-generation sequencing-based clinical sequencing: toward precision medicine in solid tumors. International journal of clinical oncology, 24(2), 115-122.
This post is written by Ximena Rodriguez (Freelancer & Content Writer).